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Charak Samhita

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क्षयं वृद्धिं समत्वं च तथैवावरणं भिषक् । विज्ञाय पवनादीनां न प्रमुह्यति कर्मसु ॥२४७॥

[Four states of dosha] The physician who understand the condition of decrease, increase, normality and occlusion of vata and other dosha, is not deluded with regard to treatment.

english translation