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Charak Samhita

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पूर्वरूपं भिषग्बुद्ध्वा व्रणानां शोफमादितः । रक्तावसेचनं कुर्यादजातव्रणशान्तये ॥४४॥

[Guidelines for management of ulcers] The physician observing shopha (swelling) as prodromal sign in the beginning should apply blood-letting to prevent the manifestation of wound.

english translation