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Charak Samhita

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सहसैव नरास्तेन परीताः शीघ्रकारिणा । विनश्यन्त्यनुपक्रान्तास्तत्र नः संशयो महान् ॥७॥

Those human who are afflicted by this acute fulminating disease succumb to death quickly, unless treated promptly. We are in great need of enlightenment concerning this disease.

english translation