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Charak Samhita

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एतैर्निदानैर्व्यामिश्रैः कुपिता मारुतादयः । दूष्यान् सन्दूष्य रक्तादीन् विसर्पन्त्यहिताशिनाम् ॥२२॥

By combination of above mentioned etiological factors, the provoked vatadi dosha affect the susceptible body elements such as rakta, lasika etc. and spread in the body in those indulged in unwholesome diet.

english translation