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Charak Samhita

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स्वतेजोऽम्बुगुणस्निग्धोद्रिक्तं मेदोऽभिजायते। पृथिव्यग्न्यनिलादीनां सङ्घातः स्वोष्मणा कृतः॥३०॥

[Formation of meda dhatu] Because of the action of medo-dhatvagni on the excessively dominant snigdha attribute of aṃbu, the meda dhatu is formed [Formation of asthi dhatu] Because of the action of asthi dhātvagni on the aggregation of prithvi, agni and anila, roughness is attained during the formation of the asthi

english translation