Charak Samhita

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कृशस्य रोगैरबलस्य यो भवेदुपद्रवैर्वा वमिपूर्वकैर्युतः| स हन्ति मर्मानुगतोऽथ राजिमान् परिस्रवेद्धीनबलस्य सर्वगः ||१५||

sanskrit

[Symptoms of bad prognostic of edema] The edema/swelling of the patient, whose body is emaciated and weakened by a disease or is debilitated, or having complications or associated with vomiting, involving vital organs or whole body or spread with prominent vessels or in which profuse discharge oozes out, leads to death

english translation

kRzasya rogairabalasya yo bhavedupadravairvA vamipUrvakairyutaH| sa hanti marmAnugato'tha rAjimAn parisraveddhInabalasya sarvagaH ||15||

hk transliteration