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Charak Samhita

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उपेक्षिते भवेत्तस्मिन्ननुबन्धो हि यक्ष्मणः। प्रागेवागमनात्तस्य तस्मात्तं त्वरया जयेत् ॥९५॥

[Need for prompt attention] If the patient suffering from kshatakshina is not given appropriate treatment on time, then this may lead to rajayakshma. Therefore well before the appearance of rajayakshma, the kshatakhsina should be treated, subdued (cured).

english translation