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Charak Samhita

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यास्तु क्षेत्रगुणैस्तेषां मध्यमेन च कर्मणा। मृदुवीर्यतरास्तासां विधिर्ज्ञेयः स एव तु ॥११॥

These divine herbs produce milder effect in case of different habitat, subject and mode of administration through the method of intake in the same for all.

english translation

Chapter 1

Section 4

Verse 12