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Charak Samhita

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तपसा ब्रह्मचर्येण ध्यानेन प्रशमेन च। रसायनविधानेन कालयुक्तेन चायुषा ॥७॥

In ancient times, the great sages attained stable life span by using the Rasayana treatment properly and timely due to penance,

english translation