Astanga Hrudaya
मुहुश्चिद्राणि विमृशन्नातुरो न स जीवति । मृत्यवे सहसार्तस्य तिलकव्यङ्गविप्लवः ॥ १२० ॥
The patient who intently and repeatedly examines or scratches his body orifices (such as the ears, nose, anus, urethra, or mouth) does not survive. Fatal signs based on the sudden appearance of black moles etc. : Sudden appearance of tila (black moles), vyanga (black patches), piplu (discoloured rashes)
english translation
muhuzcidrANi vimRzannAturo na sa jIvati । mRtyave sahasArtasya tilakavyaGgaviplavaH ॥ 120 ॥
hk transliteration by Sanscript