Charak Samhita

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ते भेषजमयोगेन कुर्वन्त्यज्ञानमोहिताः । व्याधितानां विनाशाय क्लेशाय महतेऽपिवा ॥६॥

These ignorant ones, by administering improper remedies, cause end of the patient or severe misery to the patient.

english translation