Charak Samhita

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अतिप्रवृत्तिः सङ्गो वा सिराणां ग्रन्थयोऽपि वा| विमार्गगमनं चापि स्रोतसां दुष्टिलक्षणम् ||२४||

[Four features of srotas morbidity] Increased flow or obstruction or formation of nodules and flow of bodily fluids or contents in the wrong or opposite direction are the features of morbidity of srotas.

english translation

atipravRttiH saGgo vA sirANAM granthayo'pi vA| vimArgagamanaM cApi srotasAM duSTilakSaNam ||24||

hk transliteration by Sanscript