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Charak Samhita

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तन्महत् ता महामूलास्तच्चोजः परिरक्षता। परिहार्या विशेषेण मनसो दुःखहेतवः ॥१३॥

The heart, the great vessels, and the ojas need to be protected and preserved. To achieve this, one has to avoid causes of mental suffering especially.

english translation