विरुद्धं देशतस्तावद्रूक्षतीक्ष्णादि धन्वनि। आनूपे स्निग्धशीतादि भेषजं यन्निषेव्यते ॥८८॥
If in an arid zone rough and sharp substances, and in marshy region unctuous and cold ones are used, those would be known to be antagonistic in terms of place.
english translation
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