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Charak Samhita

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भवन्ति चात्र श्लोकाः- यत् किञ्चिद्दोषमास्राव्य न निर्हरति कायतः। आहारजातं तत् सर्वमहितायोपपद्यते ॥८५॥

[Definition of viruddha (incompatibility)] The entire (drug or) diet that excites the dosha but does not eliminate it out of the body, is harmful.

english translation