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Charak Samhita

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भावहेतुः स्वभावस्तु व्याधीनां पुरुषस्य च। खरद्रवचलोष्णत्वं तेजोन्तानां यथैव हि ॥२१॥

The intrinsic nature alone (svabhava) is the cause of the existence of living beings and their diseases just as roughness (khara), fluidity (drava), mobility (chalatva) and heat (ushnatva) are respectively the intrinsic nature (or svabhava) of prithvi, apa, vayu and tejas.”

english translation