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Charak Samhita

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मदमूर्च्छायसन्न्यासास्तेषां विद्याद्विचक्षणः। यथोत्तरं बलाधिक्यं हेतुलिङ्गोपशान्तिषु ॥२७॥

This leads to various diseases such as mada (intoxication), murchcha (syncope), and sanyasa (coma) which are etiologically,

english translation