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Charak Samhita

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siva.sh/caraka-samhita/sutra-sthana/16/19

जरां कृच्छ्रेण लभते चिरं जीवत्यनामयः। तस्मात् संशोधनं काले युक्तियुक्तं पिबेन्नरः ॥१९॥

Therefore, one should take recourse to a skillfully administered purificatory therapy at an appropriate time.

english translation

Chapter 16

Verse 20