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Charak Samhita

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विद्यात् स्वाभाविकं षण्णां धातूनां यत् स्वलक्षणम्। संयोगे च वियोगे च तेषां कर्मैव कारणम् ॥१२॥

The natural theory of birth is that the six dhatus (five basic elements- prithvi, apa, tejas, vayu, akasha and the atman (soul)) possess specific qualities, and that the combination and separation of these basic elements, conditioned by the actions of the atman, determines the qualities of the individual at birth.

english translation