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Charak Samhita

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यथा विषं यथा शस्त्रं यथाऽग्निरशनिर्यथा। तथौषधमविज्ञातं विज्ञातममृतं यथा ॥१२४॥

Importance of judicious use of medicine: A drug that is understood perfectly can be used as an ambrosia. But the use of a drug that is not understood perfectly may work as poison, weapon, fire or a "bolt of thunder".

english translation