Charak Samhita

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प्रज्ञापराधो विषमास्तथाऽर्था हेतुस्तृतीयः परिणामकालः। सर्वामयानां त्रिविधा च शान्तिर्ज्ञानार्थकालाः समयोगयुक्ताः ॥४०॥

Intellectual error (prajnaparadha), unbalanced use of senses and temporal effects- these three are the causes of all disorders. Similarly, the remedy of all disorders lies in the balanced use of intellect, senses and time.

english translation

prajJAparAdho viSamAstathA'rthA hetustRtIyaH pariNAmakAlaH। sarvAmayAnAM trividhA ca zAntirjJAnArthakAlAH samayogayuktAH ॥40॥

hk transliteration by Sanscript