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Charak Samhita

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भृशं पूत्यतिमात्रं च सर्वोपद्रववच्च यत्। बलमांसक्षये यच्च तच्च रक्तमसिद्धिमत् ॥२५॥

and associated with all the complications, particularly in weak and emaciated patients is incurable.

english translation