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Charak Samhita

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इह खलु हेतुर्निमित्तमायतनं कर्ता कारणं प्रत्ययः समुत्थानं निदानमित्यनर्थान्तरम् तत्त्रिविधम्- असात्म्येन्द्रियार्थसंयोगः, प्रज्ञापराधः, परिणामश्चेति ॥३॥

[Principles of knowledge of disease Synonyms of Nidana (causative factors) and its types] Hetu, nimitta, ayatana, karta, karana, pratyaya and samutthana are synonyms of nidana (causative factors). Nidana is of three types: Asatmyendriyarthasamyoga (unsuitable contact of sense organs with their objects) Prajnaparadha (intellectual errors or knowingly engaging in harmful activities), and Kala (time, seasonal, temporal factors).

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