Charak Samhita

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दुर्बलोऽपि महादोषो विरेच्यो बहुशोऽल्पशः। मृदुभिर्भेषजैर्दोषा हन्युर्ह्येनमनिर्हृताः॥६९॥

When the amount of morbid dosha is high in a weak person, then the dosha can be eliminated by repeated administration of mild drugs. If not, this morbid dosha may end the life.

english translation