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Charak Samhita

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सर्पींषि तिक्तकानि च यच्चान्यद्रक्तपित्तनुत् [१] कर्म। बाह्याभ्यन्तरमग्र्यं तत् कार्यं पित्तकुष्ठेषु ॥५९॥

Ghee fortified with tikta (bitter) drugs and line of treatment of raktapitta should be followed internally and externally for treatment of pittaja kushtha.

english translation