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Charak Samhita

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रक्तपित्तातिवृद्धत्वात् क्रियामनुपलभ्य च। यदि गुल्मो विदह्येत शस्त्रं तत्र भिषग्जितम् ॥३९।

In case of excessive increase of pitta and rakta or due to unavailability of proper treatment, if suppuration occurs then surgery should be performed by the surgeon

english translation