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Charak Samhita

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ज्वरः प्राणान्तकृद्यश्च शीघ्रमिन्द्रियनाशनः। सप्ताहाद्वा दशाहाद्वा द्वादशाहात्तथैव च ॥५१॥

[Asadhya (incurable) jwara] Jwara having the following characteristics are incurable and lead to death – 1. Which is caused by either greater amount of / strong etiological factors 2. Which manifests with many clinical features 3. Which destroys the sense organs immediately.

english translation