Charak Samhita
चिरात् पाकश्च दोषाणां सन्निपातज्वराकृतिः। दोषे विबद्धे नष्टेऽग्नौ सर्वसम्पूर्णलक्षणः ॥१०९॥
r. The doshas undergo paka after a very long time (conversion into the healthy state of the doshas do not occur early). [Prognosis of sannipata jwara] If there is obstruction (or non – elimination) of the dosha, the agnis are completely destroyed and if all the signs and symptoms are fully manifested, then sannipata jwara is incurable; otherwise it is treatable with difficulty.
english translation
cirAt pAkazca doSANAM sannipAtajvarAkRtiH। doSe vibaddhe naSTe'gnau sarvasampUrNalakSaNaH ॥109॥
hk transliteration by Sanscript