मात्राया न व्यवस्थास्ति व्याधिं कोष्ठं बलं वयः । आलोच्य देशकालौ च योज्या तद्वच्च कल्पना ॥ १२ ॥
"There is no fixed/ rigid arrangement of the dose, these should be determined after considering the disease, nature of the alimentary tract of the patient, his strength and age, the land (nature of) and time (season), incorporate same rule for kalpana (recipe)."
english translation
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