Charak Samhita
मात्राकालक्रियाभूमिदेहदोषगुणान्तरम् । प्राप्य तत्तद्धि दृश्यन्ते ते ते भावास्तथा तथा ॥४६॥
This is, however, not a cardinal rule, and food articles and drugs do have a variety of effects depending on the dosage, time, mode of preparation, geographical location, the body constitution of the patient, and dosha.
english translation
mAtrAkAlakriyAbhUmidehadoSaguNAntaram । prApya tattaddhi dRzyante te te bhAvAstathA tathA ॥46॥
hk transliteration by Sanscript