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Charak Samhita

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तस्माद्विकारप्रकृतीरधिष्ठानान्तराणि च। समुत्थानविशेषांश्च बुद्ध्वा कर्म समाचरेत् ॥४६॥

Hence one should initiate any treatment after acquiring complete knowledge of the nature of the disease as well as its pathogenesis, location and etiological factors.

english translation