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Charak Samhita

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विपरीतगुणैर्देशमात्राकालोपपादितैः। भेषजैर्विनिवर्तन्ते विकाराः साध्यसम्मताः ॥६२॥

Fundamental principle of disease management and prognosis: Curable disorders can be treated using drugs having opposite properties and administered with due consideration to place or location, dosage and time.

english translation

Chapter 1

Verse 63