Ashtanga Hrudaya, compiled by the physician Vagbhata in the early medieval period, synthesizes the classical Ayurvedic canon. Its Kalpa-sthana — the sixth section — is a practical pharmacopeia: concise sutras on preparing, preserving and dosing medicines, methods of compounding herbal, mineral and lipid-based therapies, protocols for tonics (rasayana) and aphrodisiacs (vajikarana), and guidance on poisons and their antidotes. Key themes are formulation technique, drug compatibility, safety and emergency management. Kalpa-sthana bridges theory and bedside care, grounding therapeutic art in repeatable practice. Today it informs herbal pharmaceutics, quality and safety standards, and integrative approaches to rejuvenation and toxicology, reminding clinicians that efficacy depends as much on skilful preparation as on diagnosis.